Until the last Intune update (week of July 2, 2018), when you were setting up a Windows 10 Device Compliance Policy you were obliged to use Windows Defender as local antivirus solution if you wanted to set an antivirus solution is required to be marked as compliant.
After this update, you can now set this requirement even if you are using a third party antivirus solution (such as Symantec) as soon as this antivirus solution can be and is registered with Windows Security Center (which should be the case for most solution)