With Windows 8, users are able to connect to their Exchange mailbox without using Outlook client thanks to the Windows 8 Mail App.

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The Windows 8 Mail App is connecting to Exchange using ActiveSync protocols; doing so, any Mobile Device and ActiveSync policies will be applied to your Windows 8 device.

This means also all end-users ActiveSync functionalities are also available: your Windows 8 device will be shown in the Mobile section of your Exchange mailbox control panel (ECP) under the WindowsMail name.

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Things said, now if you try to Wipe the device because you loose it and want to reset it, the Wipe process will ONLY remove the account from the Windows 8 Mail app and will not wipe the device as it will be done with Windows Phone/Mobile device.