As you may already know, when you have a file system antivirus software installed on a server you have to define some exclusions (path and/or process).

If you work with Exchange, SQL or SharePoint, this is something you may already have done and configured; but for those who are working with ISA, TMG, IAG or UAG, you have also to configure some antivirus exclusions.

But, while there is a Microsoft KB to explain what has to be excluded from antivirus scanning for Exchange, SQL or SharePoint, it may be difficult to find these information for edge security server (ISA, TMG, IAG or UAG).

You can find ALL information required for configuring antivirus exclusion here